Plan Your Meeting

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NOVEMBER 2, 2016 (WEDNESDAY)
07:30 AM AUTONOMIC DISORDERS WORKSHOP FOR GENERALISTS (7:30 AM-5:30 PM)

Room: Coronado AB
separate registration required

01:00 PM UCNS AUTONOMIC DISORDERS CERTIFYING EXAMINATION REVIEW COURSE (1:00-5:00 PM)

Room: Marina Room
separate registration required

07:30 PM POSTER SESSION I (7:30-9:00 PM)

Trainee Poster Competition Judges:  Mark Chapleau, Victoria Claydon, Roy Freeman, Qi Fu, David Jardine, Horacio Kaufmann, Lucy Norcliffe-Kaufmann, Vera Novak, Satish Raj, David Robertson, Wolfgang Singer & Jens Tank

Room: CORONADO CDE


ORTHOSTATIC HYPOTENSION & SYNCOPE


Poster #1
Effect of droxidopa on fear of falling
L.A. Hewitt, S. Isaacson, C. François, G. Peng, G.J. Rowse
Deerfield, IL, USA

Poster #2
The new face of baroreflex failure in 2016
K. Carter, B.D. Levine
Dallas, TX, USA

Poster #3
Utility of electroencephalography (EEG) during tilt table evaluation for syncope
S. Muppidi, M. Miglis, B. Razavi, S. Jaradeh
Palo Alto, CA, USA

Poster #4
Dissociation between peripheral hemodynamic responses and central regulatory autonomic feedback mechanisms in treated hypertensive patients during orthostasis in comparison to healthy control subjects
S.F.S. Al-Rawas, H.N. Al-Mahrouqi
Muscat, Oman

Poster #5
Orthostatic heart rate changes in young patients with vasovagal syncope
M.S. Medow, S. Merchant, M. Suggs, C. Terilli, J.M. Stewart
Valhalla, NY, USA

Poster #6
Cardiovascular components of pressor response to isometric handgrip exercise in vasovagal syncope
J. Idiaquez, J.F. Idiaquez, R. Iturriaga
Vina del Mar, Chile

Poster #7
The relationship between symptoms and blood pressure in individuals with orthostatic hypotension
C. Gibbons, R. Freeman
Boston, MA, USA

Poster #8
Progressive orthostatic hypotension and reduced vasomotor reactivity in patients with vasovagal syncope
O. Mamontov, A.V. Kozlenok, M.I. Bogachev, E. Shlyakhto
St. Petersburg, Russia

Poster #9
Implementing a program to reduce the burden of orthostatic hypotension in patients of a neurology clinic
M.K. Jeroudi, M. Chang, S. Philip, P. O’Suilleabhain
Dallas, TX, USA

Poster #10
Cerebrovascular responses to the Valsalva maneuver in pediatric patients with vasovagal syncope
B.C.D. Hockin, M.G. Lloyd, C.L. Protheroe, K. Armstrong, S. Sanatani, V.E. Claydon
Burnaby, BC, Canada

Poster #11
Usefulness of lower body negative pressure in the clinical autonomic laboratory
J.A. Palma, L. Norcliffe-Kaufmann, C. Fuente Mora, J. Martinez, H. Kaufmann
New York, NY, USA

GENETIC AUTONOMIC DISORDERS

Poster #12
Familial dysautonomia: a disease with hidden tears
C. Mendoza-Santiesteban, L. Norcliffe-Kaufmann, J.A. Palma, H. Kaufmann
New York, NY, USA

Poster #13
Afferent baroreflex failure and lack of nocturnal blood pressure dipping: a mystery solved?
J. de Jong, L. Norcliffe-Kaufmann, B. Tijero, J.-A. Palma, H. Kaufmann
Amsterdam, The Netherlands

Poster #14
Serum chloride levels and electrodermal activity in hereditary sensory and autonomic neuropathy type III
J. Martinez, J.A. Palma, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA

Poster #15
Beta-adrenergic agonists vs. anti-cholinergics in obstructive lung disease in familial dysautonomia: A controlled clinical trial
L. Norcliffe-Kaufmann, B. Bar-Aluma, C. Fuente Mora, J. Martinez, O. Efrati, H. Kaufmann
New York, NY, USA

AUTONOMIC FAILURE

Poster #16
Predictors of response to droxidopa in patients with neurogenic orthostatic hypotension
J.A. Palma, J. Martinez, M. Perez, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA

Poster #17
Vagal and adrenergic baroreflex sensitivity induced by Valsalva Maneuver in patients of SCA1, SCA2 and SCA3
D. Tamuli, A.K. Jaryal, A.K. Srivastava, K.K. Deepak
New Delhi, India

Poster #18
The influence of subthalamic nucleus deep brain stimulation and levodopa on cardiovascular autonomic function in patients with Parkinson’s disease
K. Li, R. Haase, H. Rüdiger, M. Reimann, H. Reichmann, M. Wolz, T. Ziemssen
Dresden, Germany

Poster #19
Impedance plethysmography testing reveals different vascular responses during orthostatis in Parkinson’s disease and multiple system atrophy with parkinsonism
S. Roy, A.K. Jaryal, A.K. Srivastava, K.K. Deepak
Erlangen, Germany

Poster #20
Long-term effects of deep brain stimulation on autonomic function in patients with Parkinson’s disease
C.-C. Huang, Y.-F. Chen, W.-F. Chen, F.-Y. Shih, Y.-Y. Chang
Kaohsiung, Taiwan

Poster #21
Repetitive somato-sensory mechanical stimulation decreases cardiovascular sympathetic activity and blood pressure in Parkinson’s disease
F. Barbic, M. Bulgheroni, M. Minonzio, R. Zamuner, C.P. Andrade, M. Corato, S. Lalli, F. Dipaola, R. Furlan
Rozzano, Italy

Poster #22
Electrodermal activity in synucleinopathies
J. Martinez, J.A. Palma, J.C. Gomez-Esteban, L. Norcliffe-Kaufmann, A. González, M.A. Acera, B. Tijero, I. Gabilondo, H. Kaufmann
New York, NY, USA

Poster #23
REM behavior disorder in pure autonomic failure
M.G. Miglis, S. Muppidi
Palo Alto, CA, USA

Poster #24
Growth hormone responses to clonidine stimulation differentiates between multiple system atrophy and pure autonomic failure
V. Iodice, F. Valerio-Silva, L. Watson, A. Owens, C.J. Mathias, E. Vichayanrat
London, UK

Poster #25
Haemodynamic responses to the somatostatin analogue, octreotide, in patients with pre and post ganglionic lesions of the autonomic nervous system
F. Valerio-Silva, E. Vichayanrat, G.T. Ingle, E.M. Hagen, C.J. Mathias, V. Iodice
London, UK

Poster #26
AAS-Lundbeck Travel Fellowship Award
Pure autonomic failure and Lewy body dementia: red flags of evolution to a widespread alpha synucleinopathy
F. Valerio-Silva, E. Vichayanrat, A. Owens, L. Watson, C.J. Mathias, V. Iodice
London, UK

Poster #27
The natural history study of synucleinopathies
H. Kaufmann, L. Norcliffe-Kaufmann, G. Wenning, J.A. Palma, F. Krismer, W. Singer, V. Iodice, A. Albanese, A. Antonini, K. Bhatia, P. Cortelli, R. Freeman, R. Furlan, C. Gibbons, D.S. Goldstein, J.C. Gomez-Esteban, A. Iranzo, S. Jaradeh, U.J. Kang, H.J. Kim, M.R. Luquin, M. Merello, M. Miglis, P. Pastor, M.T. Pellecchia, A.C. Peltier, J. Schmahmann, C.A. Shibao, S. Vernino, R. Walsh, D. Robertson, I. Biaggioni, P.A. Low
New York, NY, USA

Poster #28
Baseline supine norepinephrine levels predict the improvement in orthostatic symptoms after atomoxetine in patients with neurogenic orthostatic hypotension
C.A. Shibao, L. Norcliffe-Kaufmann, H. Kaufmann, I. Biaggioni
Nashville, TN, USA

Poster #29
Elevated cerebrospinal fluid ratios of cysteinyl-dopamine/3,4-dihydroxyphenylacetic acid in parkinsonian synucleinopathies
D.S. Goldstein, C. Holmes, P. Sullivan, Y. Jinsmaa, I.J. Kopin, Y. Sharabi
Bethesda, MD, USA

Poster #30
Biomarkers of catecholaminergic neurodegeneration predict Parkinson’s disease. Results at 3 years of follow-up in the NINDS PDRisk study
D.S. Goldstein, C. Holmes, G.J. Lopez, T. Wu, Y. Sharabi
Bethesda, MD, USA

AUTONOMIC REGULATION: BASIC SCIENCE & ANIMAL STUDIES

Poster #31
Homeostasis, biocybernetics, and autonomic neuroscience
D.S. Goldstein, I.J. Kopin
Bethesda, MD, USA

Poster #32
Cytokine abnormalities in young patients with autonomic dysfunction
R. Martinez, J. Lankford, M.T. Numan, I.J. Butler
Houston, TX, USA

Poster #33
The impact of baroreflex on the dynamic renal vascular mechanical properties and renal circulatory regulation
T. Nishikawa, T. Arimura, K. Fujii, M. Shinoda, T. Tohyama, K. Yoshida, H. Tsutsui, K. Saku, T. Kishi, K. Sunagawa
Fukuoka, Japan

Poster #34
Identification of open loop transfer function of baroreflex using the power spectral analysis of arterial pressure
H. Mannoji, K. Saku, T. Nishikawa, T. Tohyama, Y. Oga, K. Abe, K. Kamada, T. Kishi, H. Tsutsui, K. Sunagawa
Fukuoka, Japan

Poster #35
Left ventricular hypertrophy induced heart failure inhibits the hypothalamic paraventricular nucleus neurotransmission to parasympathetic cardiac vagal neurons of the brainstem
J. Dyavanapalli, D. Mendelowitz
Washington, DC, USA

Poster #36
AAS-Lundbeck Travel Fellowship Award
Cardiac autonomic function impairment in concussed adolescents during a sit-to-stand protocol
M.E. Moir, K.C. Abbott, S.A. Fischer, J. Elfassy, L.K. Fischer, D.D. Fraser, J.K. Shoemaker
London, ON, Canada

Poster #37
Unable to attend

Poster #38
Imidazoline receptor agonist rilmenidine reverses synergistic pro-oxidant actions of angiotensin II and MsrA deficiency: implications in dysautonomia and hypertension
R. Sabharwal, R.N. El Accaoui, R.M. Weiss, M.K. Davis, F.M. Abboud, M.W. Chapleau
Iowa City, IA, USA

Poster #39
Ang-(1-7) improves autonomic function, delays disease progression, and increases lifespan in superoxide dismutase 1 (SOD1) mice with amyotrophic lateral sclerosis
L. Yang, L. Gutmann, R. Sabharwal
Iowa City, IA, USA

Poster #40
Autonomic influence on myocardial repolarisation analysed from T-waves in the ECG
A.-B. Mehlsen, M. Cesario, H.B.D. Soerensen, J. Mehlsen
Copenhagen, Denmark

POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME

Poster #41
Is autonomic dysfunction a possible side effect to vaccination against human papilloma virus?
J. Mehlsen, K. Pors, L.S. Brinth
Frederiksberg, Denmark.

Poster #42
Electrodermal activity during head-up tilt in patients with POTS
S. Balegh, M. Robin, J. Benoit, B. Ditto, R. Schondorf
Montrea, QC, Canada

Poster #43
Ivabradine: a potential treatment in postural orthostatic tachycardia syndrome (POTS)
H. Mistry, S. Eziukwu, M.M. Ahsan, A. Butt, S. Hamid, A. Suleman
McKinney, TX, USA

Poster #44
Nutcracker syndrome of left renal vein in postural orthostatic tachycardia syndrome (POTS)
H. Mistry, S. Lingampally, A. Butt, S. Hamid, S. Eziukwu, A. Suleman, J. Bard
McKinney, TX, USA

Poster #45
A case report on a novel mutation in Ehlers-Danlos syndrome (EDS) and postural orthostatic tachycardia syndrome (POTS)
H. Mistry, S. Eziukwu, A. Butt, A. Suleman
McKinney, TX, USA

Poster #46
A case study on the usefulness of autonomic test screening in Lyme disease
H. Mistry, M.M. Ahsan, A. Butt, S. Eziukwu, A. Suleman, R. Wilson
McKinney, TX, USA

Poster #47
Therapeutic trial of Midodrine in non-postural orthostatic tachycardia syndrome (POTS) patients with orthostatic intolerance
S. Eziukwu, H. Mistry, M.M. Ahsan, A. Butt, A. Suleman
McKinney, TX, USA

Poster #48
Heart rate dynamics in postural orthostatic tachycardia syndrome
P. Kumar, S. Gupta , B. Kaul, S. Raghavan
New Delhi, India

Poster #49
Quantitative assessment of autonomic symptom burden in postural tachycardia syndrome
M. Friesz, N. Rea, C.L. Campbell, E.Palmer, M.M. Cortez
Salt Lake City, UT, USA

Poster #50
Biofeedback intervention in pediatric patients with postural orthostatic tachycardia syndrome (POTS)
K.J. Homan, C. Harbeck-Weber, M. Hord, J. O’Connor
Rochester, MN, USA

Poster #51
Vagal dysfunction in patients with neuropathic POTS
G. Jacob, L. Diedrich, K. Sato, S.R. Raj, D. Robertson, I. Biaggioni, A. Diedrich
Tel Aviv, Israel

Poster #52
Chronic intravenous hydration as a treatment for adults with refractory postural orthostatic tachycardia syndrome
D.S. Saperstein
Phoenix, AZ, USA

Poster #53
“Which came first – the chicken or the egg?” Vitamin D deficiency in POTS patients
A. Luehrs, C.-A. Haensch
Moenchengladbach, Germany

Poster #54
The diagnostic experience in postural tachycardia syndrome: insights from a cross-sectional community-based survey
S.R. Raj, L. Stiles, B. Shaw, E.A. Green, C.A. Dorminy, C.A. Shibao, L.E. Okamoto, E.M. Garland, A. Gamboa, A. Diedrich, I. Biaggioni, D. Robertson
Calgary, AB, Canada

Poster #55
Carbidopa fails to decrease urinary sodium excretion or improve orthostatic tachycardia in postural tachycardia syndrome
E.M. Garland, J.E. Celedonio, V. Nwazue, S.Y. Paranjape, B.K. Black, A. Diedrich, D. Robertson, S.R. Raj
Nashville, TN USA

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NOVEMBER 3, 2016 (THURSDAY)
08:00 AM CONTINENTAL BREAKFAST (8:00-8:30 AM)

Room: Coronado CDE

08:30 AM Plenary Lecture (8:30-9:30 AM)

Chairs: Qi Fu
Room: Coronado AB


Influences of female reproductive hormones on regulation of body temperature and blood pressure in humans
Nisha Charkoudian, Ph.D.
Natick, MA, USA

09:30 AM SESSION 1: AUTOIMMUNE AUTONOMIC NEUROPATHY SYMPOSIUM (9:30-11:00 AM)

SPONSORED BY NuFACTOR

Chairs: Chris Gibbons & Wolfgang Singer
Room: Coronado AB


9:30-10:00 AM
Invited Expert Speaker
Autoimmune autonomic disorders
Steve Vernino, M.D., Ph.D.
Dallas, TX, USA


10:00-10:15 AM
AAS-Lundbeck Travel Fellowship Award
Dysautonomia due to ganglionic nicotinic acetylcholine receptor autoimmunity
J.K. Cutsforth-Gregory, E.A. Coon, D.M. Sletten, A. McKeon, M. Suarez, P. Sandroni, W. Singer, E.E. Benarroch, R.D. Fealey, P.A. Low
Rochester, MN, USA


10:15-10:30 AM
Seronegative autoimmune autonomic neuropathy is clinically distinct from autoimmune autonomic ganglionopathy
E. Golden, S. Vernino
Dallas, TX, USA


10:30-10:45 AM
AAS-Lundbeck Travel Fellowship Award
The prevalence of ganglionic AChR antibodies in postural tachycardia syndrome (POTS)
S. Vernino, M. Bryarly, S. Hopkins, L.E. Okamoto, B.K. Black, S.Y. Paranjape, S.R. Raj
Dallas, TX, USA


10:45-11:00 AM
AT1R autoantibodies in postural tachycardia syndrome
X. Yu, H. Li, A. Fedorowski, D.C. Kem
Oklahoma City, OK, USA

11:00 AM COFFEE BREAK (11:00-11:30 AM)

Room: Coronado CDE

11:30 AM SESSION 2: AUTONOMIC FAILURE (11:30 AM-1:00 PM)

Chairs: David Goldstein & David Robertson
Room: Coronado AB


11:30-11:45 AM
Phosphorylated and total alpha-synuclein in Parkinson disease
C. Gibbons, N. Wang, J. Garcia, L. Shih, R. Freeman
Boston, MA, USA


11:45-12:00 PM
Blood pressure-lowering effect of local passive heat in autonomic failure patients with supine hypertension
L.E. Okamoto, J.E. Celedonio, A. Gamboa, C.A. Shibao, S.R. Raj, A. Diedrich, S. Paranjape, B.K. Black, D. Robertson, C.G. Crandall, I. Biaggioni
Nashville, TN, USA


12:00-12:15 PM
Clinical characteristics of African American patients with autonomic failure
A.C. Arnold, L.E. Okamoto, B.K. Black, S.R. Raj, D. Robertson, I. Biaggioni, C.A. Shibao
Nashville, TN, USA


12:15-12:30 PM
Dysautonomic syndrome and heart rate variability in patients of spinocerebellar ataxia type 2 with different clinical stages
G. Sánchez-Cruz, L. Velázquez-Pérez, J.M. Iglesias, L.E. Almaguer-Mederos Holguin, Cuba


12:30-12:45 PM
AAS-Lundbeck Travel Fellowship Award
Complexity analysis of cardiovascular oscillations in amyotrophic lateral sclerosis
B. De Maria, G. Mora, K. Marinou, R. Sideri, A. Porta, R. Furlan, L. Dalla Vecchia
Milan, Italy


12:45-1:00 PM
The natural history of pure autonomic failure: a US prospective cohort
H. Kaufmann, L. Norcliffe-Kaufmann, J.A. Palma, I. Biaggioni, P. Low, W. Singer, D. Goldstein, A. Peltier, C. Shibao, C. Gibbons, R. Freeman, D. Robertson, on behalf of the Autonomic Disorders Consortium
New York, NY, USA

01:00 PM FREE TIME (1:00-4:00 PM)
04:00 PM CLINICAL AUTONOMIC RESEARCH EDITORIAL BOARD MEETING (4:00-5:00 PM)

Nautical

05:00 PM TRAINEE SOCIAL (5:00-6:00 PM)

Room: Coronado Terrace

06:00 PM STREETEN LECTURE (6:00-7:00 PM)

Chairs: David Jardine
Room: Coronado AB


Recruitment strategies in efferent sympathetic nerve activity: old hypotheses gain momentum in human multi-unit recordings
J. Kevin Shoemaker, Ph.D.
London, ON, Canada

07:00 PM AWARDS SESSION (7:00 – 7:45 PM)

Chairs: Victoria Claydon, Chris Gibbons & Lucy Norcliffe-Kaufmann
Room: Coronado AB


7:00-7:15 PM
Streeten Travel Fellowship Award
Carotid body denervation prevents the worsening of cardiac function and heart failure in rat models of myocardial infarction and hypertension
K. Fujii, Y. Oga, A. Nishizaki, T. Takehara, T. Akashi. K. Saku, K. Sunagawa. T. Kishi
Fukuoka, Japan


7:15-7:30 PM
FMS/Peňáz Wesseling Travel Fellowship Award
The optimal intermittent calf compression paradigm to improve orthostatic fluid shifts and cardiovascular control
B.C.D. Hockin, G.K. Brar, I.A. Ruiz-Romero, V.E. Claydon
Burnaby, BC, Canada


7:30-7:45 PM
FMS/Peňáz Wesseling Travel Fellowship Award
Baroreflex sensitivity impairment during hypoglycemia is associated with an increase in interleukin-6
B.M.W. Illigens, A.D. Rao, I. Bonyhay, S. Ballatori, M. Casasola, C.H. Gibbons, G. K. Adler, R. Freeman
Boston, MA, USA

07:45 PM AAS-Lundbeck Travel Fellowship Prize Presentations & Fellow of the American Autonomic Society Presentations (7:45-8:00 PM)
08:00 PM POSTER SESSION II (8:00-9:30 PM)

Trainee Poster Competition Judges: Eduardo Benarroch, Italo Biaggioni, Thomas Chelimsky, William Cheshire, Chris Gibbons, David Goldstein, Max Hilz & Yrsa Sverrisdotter

Room: CORONADO CDE


CARDIOVASCULAR DISEASE, OBESITY & AGING: HUMAN STUDIES

Poster #56
Exaggerated pressor and sympathetic responses to short-duration static handgrip in coronary artery disease patients: effect of six-months of cardiac rehabilitation
M.B. Badrov, K.N. Wood, S. Lalande, N. Suskin, J.K. Shoemaker
London, ON, Canada

Poster #57
Features of the autonomic circulatory control in patients with arterial hypertension depending on concomitant migraine
O.V. Mamontov, L. Babayan, A.V. Amelin, M. Bogachev, A.A. Kamshilin
St. Petersburg, Russia

Poster #58
Relationship between cardiovagal control and diastolic blood pressure in adult Native and Mexican Americans with a history of alcohol use disorders
J.R. Criado, D.A. Gilder, M.A. Kalafut, C.L. Ehlers
La Jolla, CA, USA

Poster #59
AAS-Lundbeck Travel Fellowship Award
The pathophysiology of carotid sinus hypersensitivity: sensory block of the sternocleidomastoid muscles does not increase responses to carotid sinus massage
M.G. Lloyd, T. van Leeuwen, J. Wakeling, M. Koehle, R.J. Drapala, V.E. Claydon
Burnaby, BC, Canada

Poster #60
Sympathetic activity does not contribute to hypertension in obese African American women
C.A. Shibao, A. Marinos, J.E. Celedonio, L.E. Okamoto, C.A. Arnold, A. Diedrich, A. Gamboa, I. Biaggioni
Nashville, TN, USA

Poster #61
Cardiac-vascular properties in older women with controlled hypertension
Q. Fu, Y. Okada, S.A. Best, S.S. Jarvis, M.M. Galbreath, B.D. Levine
Dallas, TX, USA

Poster #62
Higher within-person blood pressure associated with shorter sleep duration
P.M. Macey, L. Samy, M.-L. Brecht, K.E. Macey, S. Shaboyan, M. Sarrafzadeh
Los Angeles, CA, USA

NEUROIMAGING IN BRAIN & HEART

Poster #63
Sex differences in insular cortex gyri responses to a hand grip challenge
P.M. Macey, N.S. Rieken, R. Kumar, J.A. Ogren, R.M. Harper
Los Angeles, CA, USA

Poster #64
Inter-individual sympathetic responses to experimental muscle pain: the central circuitry responsible for the increases or decreases in MSNA
S. Kobuch, A. Fazalbhoy, R. Brown, L.A. Henderson, V.G. Macefield
Penrith, Australia

DIABETIC, AUTOIMMUNE & OTHER AUTONOMIC NEUROPATHIES

Poster #65
Autonomic dysfunction in Charcot Marie Tooth disease IA
R. Bhavaraju-Sanka, P. Jones
San Antonio, TX, USA

Poster #66
Symptomatic autonomic impairment in autism spectrum disorders
B.P. Goodman, J.A. Khoury, C. Hoffman-Snyder, B.K. Woodruff
Scottsdale, AZ, USA

Poster #67
Intraepidermal nerve fiber density quantification is more sensitive method than sudomotor test for detecting early neuropathy in type 2 diabetes
E.H. Sohn, K.S. Song, A.Y. Lee
Daejeon, South Korea

Poster #68
Interaction between circadian blood pressure rhythm and autonomic nervous function in diabetic patients with chronic kidney disease
G. Yasuda, S. Komiya, T. Hase, A. Fujiwara, N. Hirawa
Yokohama, Japan

Poster #69
Effect of gastroparesis on glycemic variability in insulin-treated patients with diabetes mellitus
B. White, B.G. Theckedath, V. Nellaiappan, A. Gupta, R.   Bhattaram, J.L. Gilden
North Chicago, IL, USA

Poster #70
Unable to attend

HEALTHCARE SYSTEMS & DELIVERY IN AUTONOMIC DISORDERS

Poster #71
Autonomic neuropathy in adult Still’s disease
G.A. Cook
Portsmouth, VA, USA

GASTROINTESTINAL & UROGENITAL SYSTEMS, IBS, CYSTITIS

Poster #72
Autonomic disorders in a tertiary military referral clinic
G.A. Cook
Portsmouth, VA, USA

Poster #73
Psychophysiologic responses to a laboratory stressor in chronic pelvic pain conditions vs. healthy controls
D. Williams, J. Janata, G. Chelimsky, K. Pajer, J. Thayer, T. Chelimsky
Columbus, OH, USA

Poster #74
Chronic stress induced autonomic and mitochondria dysfunction in neuronal and non-neuronal cells: role in IC/BPS
F.A. Kullmann, A. Wolf-Johnston, B. McDonnell, A.J. Kanai, C. Corey, S. Shiva, T. Chelimsky, L. Rodriguez, L.A. Birder
Pittsburgh, PA, USA

MICRONEUROGRAPHY & CARDIOVASCULAR REFLEXES IN HUMANS

Poster #75
Head-down tilt bed rest increases sympathetic burst latency
S.A Klassen, S. De Abreu, P. Denise, J.K. Shoemaker, H. Normand
London, ON, Canada

Poster #76
Vascular sympathetic control in Sjögren syndrome
E. Brunetta, P. Mandelli, M.I.S. Achenza, E. Scannella, L. Boccassini, A. Marchi, F. Barbic, I. Bianchi, P.S. Puttini, A. Porta, R. Furlan
Rozzano, Italy

Poster #77
Can distraction play a role in sympathetic output and pain perception during experimental muscle pain?
R. Brown, S. Kobuch, V. Macefield
Campbelltown, Australia

Poster #78
Stimulation of the dorsal root ganglion (DRG) for medicine refractory chronic neuropathic pain: is there sympathetic involvement?
Y.B. Sverrisdóttir, J. Fitzgerald, A. Kent, J. Kramer, A.L. Green
Oxford, UK

Poster #79
Influences of experimental air pollution on human sympathetic nerve traffic: a double blind, randomized, twofold crossover study
K. Heusser, J. Tank, O. Holz, M. May, J. Brinkmann, A. Diedrich, T. Framke, A. Koch, A. Grosshennig, F.C.G.J. Sweep, W. Koch, N. Krug, J. Jordan, J.M. Hohlfeld
Hannover, Germany

CEREBRAL BLOOD FLOW REGULATION

Poster #80
Oscillatory lower body negative pressure impairs task related functional hyperemia in healthy volunteers
J.M. Stewart, K. Balakrishnan, P. Visintainer, Z.R. Messer, C. Terilli, M.S. Medow
Hawthorne, NY, USA

Poster #81
Influence of sex, menstrual cycle and oral contraceptives on autonomic function and cerebrovascular resistance
S. Abidi, M. Nili, S. Serna, S. Kim, H. Edgell
Toronto, ON, Canada

Poster #82
Cerebrovascular function and persistent headache after sports-related concussion: preliminary results
T. Albalawi, J.W. Hamner, W.P. Meehan III, C.O. Tan
Boston, MA, USA

Poster #83
Orthostatic cerebral hypoperfusion syndrome (OCHOs)
P. Novak
Boston, MA, USA

NOVEL THERAPIES & CLINICAL TRIALS

Poster #84
Safety and preliminary efficacy of intranasal insulin in Parkinson disease: a pilot study
P. Novak, D. Pimentel, V. Novak
Boston, MA, USA

Poster #85
Clinical observations regarding the use of ivabradine in autonomic dysfunction
A. Barboi, S. Moffat, V. Cadell, I. Furman
Glenview, IL, USA

Poster #86
Droxidopa for neurogenic orthostatic hypotension in autoimmune autonomic ganglionopathy
J.A. Palma, J. Martinez, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA

Poster #87
Blood pressure normalization with cranial nerve modulation in migraine subjects
R.M. Harper, D. Snodgrass, F. Yan-Go, J. Jen, C.R. White, R.K. Harper, M. Yazdizadeh, E.K. Sauerland
Los Angeles, CA, USA

Poster #88
Droxidopa improved attention and hyperactivity in a patient with congenital insensitivity to pain with anhidrosis (HSAN IV)
C. Fuente Mora, C. Spalink, J.A. Palma, L. Norcliffe-Kaufmann, H. Kaufmann
New York, NY, USA

Poster #89
Dexmedetomidine: a novel approach to treating refractory adrenergic crisis in familial dysautonomia
R.C. Dillon, C. Spalink, L. Norcliffe-Kaufmann, J.A. Palma, D. Altshuler,
J. Papadopoulos, H. Kaufmann
New York, NY, USA

Poster #90
Hemodynamics and muscle sympathetic nerve activity in patients with end stage heart failure before and after left ventricular assist device implantation
K. Heusser, J. Boehm, J. Brinkmann, C. Bara, A. Haverich, A. Diedrich, J. Jordan, J. Schmitto, J. Tank
Hannover, Germany

Poster #91
AAS-Lundbeck Travel Fellowship Award
Cardiac pacemaker channel (HCN4) inhibition and atrial arrhythmogenesis following acute relief of cardiac sympathetic activation
K. Chobanyan-Jürgens, K. Heusser, D. Duncker, C. Veltmann, M. May, H. Mehling, F.C. Luft, C. Schröder, J. Jordan, J. Tank
Hannover, Germany

PATIENT EDUCATION & SOCIAL MEDIA

Poster #92
How to leverage social media to advance the field of autonomic disorders
W.P. Cheshire Jr., L. Norcliffe-Kaufmann
Jacksonville, FL, USA

PEDIATRIC AUTONOMIC DISORDERS

Poster #93
Reduced vagal modulation of heart rate in pediatric functional gastrointestinal disorders (FGID)
L. Zhong, T. Chelimsky, C. Welzig, A. Silverman. G. Chelimsky
Milwaukee, WI, USA

Poster #94
Characterization of endocannabinoid (EC) changes with diffuse noxious inhibitory control (DNIC) in subjects with pediatric functional gastrointestinal disorders (FGID)
D. Wayer, T. Chelimsky, C. Hillard, A. Silverman, L. Conant, P. Simpson, C. Welzig, K. Hainsworth, G. Chelimsky
Milwaukee, WI, USA

Poster #95
AAS-Lundbeck Travel Fellowship Award
Low bioenergetics in functional disorders parallel disability score
T. Chelimsky, P. Simpson, L. Zhang, J. Banda, D. Dimock, S. Komas, E. Awe, G. Chelimsky
Milwaukee, WI, USA

Poster #96
Identification and evaluation of rare, congenital central hypoventilation syndrome (CCHS)-causing PHOX2B non-polyalanine repeat expansion mutations (NPARMs) and associated phenotypes
A. Zhou, P. Reineke, C. Moore, C.M. Rand, V. Speare, E.M. Berry-Kravis, L. Zhou, M. Yu, L.J. Jennings, D.E. Weese-Mayer
Chicago, IL, USA

SPINAL CORD INJURY & AUTONOMIC DYSFUNCTION

Poster #97
AAS-Lundbeck Travel Fellowship Award
Bowel management and quality of life following spinal cord injury: the influence of autonomic dysreflexia
V.E. Lucci, J.A. Inskip, M.S. McGrath, R. Willms, V.E. Claydon
Vancouver, BC, Canada

EXERCISE, TEMPERATURE REGULATION & HYPOXIA
Poster #98
Correlation between heart rate at rest and vagal reactivation after submaximal exercise test
G.L. Garcia, K.E. Fontana, C.J. Gomes, E.M.K.V.K. Soares, W.R. Alves, L.G.G. Porto, L.F. Junqueira Jr, G.E. Molina
Brasilia, Brazil

SYMPATHOVAGAL BALANCE & SPECTRAL ANALYSIS

Poster #99
Vestibular dysfunction in the autonomic laboratory
S. Jaradeh, S. Muppidi, M. Miglis, L. Fong, F. Luc, T. Prieto
Stanford, CA, USA

Poster #100
The relationship between parasympathetic activity and aortic blood pressures in young healthy individuals
P.L. Latchman, G.J. Gates, W. Zhu, R.S. Axtell, R. Thiel, N.S. Stachenfeld, R.E. De Meersman
New Haven, CT, USA

Poster #101
State anxiety and nonlinear heart rate variability during examination stress
E.V. Saperova, D.A. Dimitriev
Cheboksary, Russia

Poster #102
AAS-Lundbeck Travel Fellowship Award
Short- and long-term effects of Fingolimod on cardiovagal gain in patients with relapsing-remitting multiple sclerosis
S. Roy, C. de Rojas Leal, R. Wang, M. Liu, D.-H. Lee, R.A. Linker, M.J. Hilz
Erlangen, Germany

Poster #103
Central autonomic dysregulation may cause inadequate cardiovagal modulation in multiple sclerosis patients after six months of Fingolimod-treatment
M.J. Hilz, R. Wang, F. Canavese, M. Liu, C. de Rojas Leal, S. Roy, D.-H. Lee, R.A. Linker
Erlangen, Germany

Poster #104
Heart rate variability in women working in hospital: a comparison between women with and without preschool children
L. Dalla Vecchia, B. De Maria, C. Andreotti, V. Mansi, A. Porta
Milan, Italy

Poster #105
Investigating the relationship between cardiac interoception and heart rate variability via interoceptive (active) inference
A.P. Owens, K.J. Friston, D.A. Low, C.J. Mathias, H.D. Critchley
London, UK

AUTISM SPECTRUM DIORDERS

Poster #106
Clinical autonomic testing in autism spectrum disorder
A.P. Owens, V. Iodice
London, UK

Poster #107
Autonomic symptoms endorsed by adults with autism spectrum disorders
B.K. Woodruff, J.B. Adams, M. Temkit, B.P. Goodman.
Scottsdale, AZ, USA

AUTONOMIC FUNCTION TESTING

Poster #108
Validity of bedside tests for evaluating sweating in normal and anhidrotic patients
R.K. Khurana, C. Russell
Baltimore, MD, USA

LATE-BREAKING ABSTRACTS

Poster #LB1
Fingolimod-initiation in multiple sclerosis patients is associated with beneficial cardiovascular autonomic effects
R. Wang, C. de Rojas Leal, M. Liu, F. Canavese, S. Roy,
K.M. Hösl, K. Winder, D.-H. Lee, R.A. Linker, M.J. Hilz
Erlangen, Germany

Poster #LB2
Elimination of spurious absent sweat response in QSART recordings
J. Corfits, W. Singer, P. Sandroni, R.D. Fealey, E.A. Coon, E.E. Benarroch, S. Berini, M. Mauermann, D.M. Sletten, J.K. Cutsforth-Gregory, J.D. Schmelzer, P.A. Low
Rochester, MN, USA

Poster #LB3
Neurogenic versus non-neurogenic orthostatic hypotension – practical predictors for the office
H.A. Kim, D.M. Sletten, M.D. Suarez, P. Sandroni, R.D. Fealey, E.A. Coon, P.A. Low, W. Singer
Rochester, MN, USA

Poster #LB4
Autoimmunity-associated autonomic failure with sympathetic denervation
D.S. Goldstein, C. Holmes, P. Sullivan, V. Donadio, E. Zhong, R. Isonaka, Y. Sharabi
Bethesda, MD, USA

Poster #LB5
Pure autonomic failure without synucleinopathy
R. Isonaka, C. Holmes, P. Sullivan, D.S. Goldstein
Bethesda, MD, USA

Poster #LB6
Contribution of the carotid chemoreflex to sympathetic discharge patterns in healthy humans
J.K. Limberg, W.W. Holbein, M.B. Badrov, M.J. Joyner, J.K. Shoemaker
Rochester, MN, USA

Poster #LB7
Effect of aromatherapy on autonomic nervous system by using wearable devices in patients after childbirth
M. Kogure, K. Imazu, Y. Kogure, Y. Yamanouchi, J. Hirose, K. Usuku
Kumamoto, Japan

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NOVEMBER 4, 2016 (FRIDAY)
08:00 AM CONTINENTAL BREAKFAST (8:00-8:30 AM)

Room: Coronado CDE

08:30 AM Plenary Lecture (8:30-9:30 AM)

Reflex circuits in immunity
Kevin J. Tracey, M.D.
Manhasset, NY, USA
Chair: Thomas Chelimsky

Room: Coronado AB

09:30 AM SESSION 3: MULTIPLE SYSTEM ATROPHY SYMPOSIUM (9:30 AM-12:00 PM)

SPONSORED BY THE MSA COALITION

Chairs: Eduardo Benarroch & Horacio Kaufmann
Room: Coronado AB


9:30-10:00 AM
Invited Expert Speaker Update on recognition and course modifying treatment of MSA
Phillip A. Low, M.D.
Rochester, MN, USA


10:00-10:15 AM
Don Summers Memorial Multiple System Atrophy Travel Award
Cardiovascular autonomic dysfunction in autopsy-confirmed multiple system atrophy: predictors of bad and good outcome
E. Vichayanrat, E. De Plabo-Fernandez, F. Valerio-Silva, L. Watson, J. Navarro-Otano, J.L. Holton, N.P. Quinn, C.J. Mathias, V. Iodice
London, UK


10:15-10:30 AM
Don Summers Memorial Multiple System Atrophy Travel Award
Circadian blood pressure control in afferent versus efferent lesions in the arterial baroreflex
J. de Jong, L. Norcliffe-Kaufmann, J.-A. Palma, W. Wieling, H.Kaufmann
Amsterdam, The Netherlands


10:30-10:45 AM
Decreased L-aromatic-amino-acid decarboxylase activity and vesicular storage contribute to putamen dopamine depletion in Parkinson’s disease and multiple system atrophy
D.S. Goldstein, P. Sullivan, Y. Jinsmaa, C. Holmes, D.C. Mash, I.J. Kopin, Y. Sharabi
Bethesda, MD, USA


10:45-11:00 AM
Spinal fluid biomarkers for multiple system atrophy – a pilot study
W. Singer, A. Schmeichel, D.M. Goldstein, J.D. Schmelzer, A.D. Zeller, T.L. Gehrking, P.A. Low
Rochester, MN, USA

11:00 AM COFFEE BREAK (11:00-11:30 AM)
11:30 AM PRESENTATIONS FROM TOP 4 POSTERS (11:30-12:00 PM)

Chairs: Qi Fu & Satish Raj
Room: Coronado AB

12:00 PM SESSION 4: POSTURAL ORTHOSTATIC TACHYCARDIA SYNDROME (POTS) (12:00-1:30 PM)

Chairs: Qi Fu & Satish Raj
Room: Coronado AB


12:00-12:15 PM
Can we predict the course of postural orthostatic tachycardia syndrome in children?
B. Kakavand, E. Nunlist
Orlando, FL, USA


12:15-12:30 PM
The face of postural tachycardia syndrome: a cross-sectional community-based survey
S.R. Raj, L. Stiles, B. Shaw, E.A. Green, C.A. Dorminy, C.A. Shibao, L.E. Okamoto, E.M. Garland, A. Gamboa, A. Diedrich, I. Biaggioni, D. Robertson
Calgary, AB, Canada


12:30-12:45 PM
Cerebral regional oxygen saturation during head-up tilt testing (HUT) in children and adolescents with postural orthostatic tachycardia syndrome (POTS) and matched controls
C. Panicker, A. Sadowski, S. Rizvydeen, C.M. Rand, M.S. Carroll, N.L. Kuntz, D.E. Weese-Mayer
Chicago, IL, USA


12:45-1:00 PM
AAS-Lundbeck Travel Fellowship Award
Assessment of vascular endothelial function in postural tachycardia syndrome and healthy controls
J.E. Celedonio, V. Nwazue, R. Figueroa, S.Y. Paranjape, B.K. Black, E.M. Garland, L.E. Okamoto, C.A. Shibao, D. Robertson, A. Diedrich, S.R. Raj, I. Biaggioni, A. Gamboa
Nashville, TN, USA


1:00-1:15 PM
Role of sleep disturbances in children with autonomic complaints
K. Gundrum, T.C. Chelimsky, N.A. Norins, P. Simpson, M. Nugent, G. Chelimsky
Milwaukee, WI, USA


1:15-1:30 PM
Characteristics of POTS patients in a large pediatric program
J.R. Boris, T. Bernadzikowski
Philadelphia, PA, USA

01:30 PM FREE TIME (1:30-7:00 PM)
01:30 PM AAS BOARD MEETING (1:30-3:30 PM)

Room: Nautical


05:30 PM AAS COMMITTEE MEETINGS (5:30-6:30 PM)

Room: Nautical


06:50 PM PRIZE WINNERS PHOTO SESSION (6:50-7:00 PM)

Roy’s San Diego Waterfront (333 W Harbor Drive, San Diego, CA 92101)
(for sponsors and awardees of travel awards, research fellowships and poster presentation prizes)


07:00 PM PRESIDENTIAL DINNER (7:00-10:00 PM)

Roy’s San Diego Waterfront (333 W Harbor Drive, San Diego, CA 92101)

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NOVEMBER 5, 2016 (SATURDAY)
08:00 AM CONTINENTAL BREAKFAST (8:00-8:30 AM)

Room: Coronado CDE

08:30 AM AAS BUSINESS MEETING (8:30-9:00 AM)

Room: Coronado AB

09:00 AM SESSION 5: ORTHOSTATIC HYPOTENSION & SYNCOPE (9:00 – 10:45 AM)

Chairs: Max Hilz & Jens Tank
Room: Coronado AB


9:00-9:15 AM
Cardiovascular regulatory profile in subjects with constitutional hypotension
G. Jacob, F. Barbic, F. Dipaola, M. Glago, A. Porta, R. Furlan
Tel Aviv, Israel


9:15-9:30 AM
Post-synaptic α1-adrenergic vasoconstriction is impaired in young patients with vasovagal syncope and is corrected by nitric oxide synthase inhibition
J.M. Stewart, R. Sutton, M. Suggs, S. Merchant, C. Terilli, P. Visintainer, M.S. Medow
Hawthorne, NY, USA


9:30-9:45 AM
Durability of effect with long-term droxidopa treatment in patients with symptomatic neurogenic orthostatic hypotension
L.A. Hewitt, S. Isaacson, J. Lisk, G. Liang, G.J. Rowse
Deerfield, IL, USA


9:45-10:00 AM
Can blood pressure responses to the Valsalva maneuver predict orthostatic hypotension?
W. Singer, T.L. Gehrking, D.M. Sletten, J.A. Gehrking, P.A. Low
Rochester, MN, USA


10:00-10:15 AM
Sit-to-stand testing can effectively measure orthostatic vitals and diagnose orthostatic hypotension when lower diagnostic cut-offs are used
B.H. Shaw, E.M. Garland, B.K. Black, S.Y. Paranjape, C.A. Shibao, L.E. Okamoto, A. Gamboa, A. Diedrich, I. Biaggioni, D. Robertson, S.R. Raj
Calgary, AB, Canada

10:15 AM COFFEE BREAK (10:15-10:45 AM)

Room: Coronado CDE

10:45 AM SESSION 6: DIABETIC & AUTONOMIC NEUROPATHY (10:45AM – 12:00PM)

Chairs: Roy Freeman & Janice Gilden
Room: Coronado AB


10:45-11:00 AM
Treatment induced neuropathy of diabetes: an autonomic dysrecognition syndrome
C.H. Gibbons
Boston, MA, USA


11:00-11:15 AM
Prevalence of autonomic neuropathy in the metabolic syndrome compared to impaired glucose tolerance
L. Zilliox, D.M.P. Morado, S. Dunlap, J.W. Russell
Baltimore, MD, USA


11:15-11:30 AM
Association of hyperglycemia with autonomic dysfunction during sleep in patients with obstructive sleep apnea (OSA) and mild hyperglycemia
A. Peltier, K. Bagai, R. Harder, F. Iqbal, E.M. Garland, B.A. Malow, D. Robertson, A. Diedrich
Nashville, TN, USA


11:30-11:45 AM
Epidermal and dermal neurovascular quantification in patients with type 2 diabetes
B.C. Suh, E. Sohn, M. McCormick, N. Wang, C. Gibbons, R. Freeman
Seoul, Korea


11:45-12:00 PM
Statins exert an antiarrhythmic effect in an animal model of ventricular arrhythmia after myocardial infarction in Type I diabetes: reversal of autonomic imbalance and calcium alternans
C.M. Welzig, H. Jin, M. Rajab, A. Albano, B. Wang, M. Aronovitz, R. Blanton, M. Link, H. Park, S.F. Neujaim, J.B. Galper
Milwaukee, WI, USA

12:00 PM CLOSING REMARKS (12:00-12:15 PM)

Dr. Chris Gibbons
President, American Autonomic Society

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