Felicia Axelrod: 2019 Awardee

img

Felicia Axelrod: 2019 Awardee

 

Awardee: Amy C. Arnold, Ph.D.


Amy C. Arnold, Ph.D. is the 2019 recipient of the Felicia Axelrod Investigator Award. Dr. Arnold is Assistant Professor of Neural and Behavioral Sciences at the Pennsylvania State University College of Medicine, as well as Adjunct Assistant Professor in the Autonomic Dysfunction Center and Division of Clinical Pharmacology at the Vanderbilt University Medical Center. Dr. Arnold has been involved in autonomic research since 2005, when she was a graduate student in the Hypertension and Vascular Research Center at Wake Forest University. She then completed a postdoctoral fellowship in Clinical Pharmacology and a Master’s of Science degree in Clinical Investigation at Vanderbilt. Dr. Arnold’s translational research program examines the neural mechanisms of blood pressure regulation, with the ultimate goal of developing more targeted treatment approaches for cardiovascular-related diseases. Her research over the past decade has focused on the role of the renin-angiotensin system, and in particular the beneficial hormone angiotensin-(1-7), in cardiovascular autonomic regulation using both experimental animal models and human subjects. Dr. Arnold’s research has also examined underlying mechanisms and treatment approaches for supine hypertension in primary autonomic failure, as well as defined the nature of cognitive dysfunction or “brain fog” in postural tachycardia syndrome. Of particular importance, her research has shown that the renin-angiotensin system contributes to supine hypertension in autonomic failure, even in the absence of its rate-limiting enzyme renin, a finding that has altered treatment of these patients. The National Institutes of Health, American Heart Association, Dysautonomia International, and Central Society for Clinical and Translational Research have generously funded her research.