Two NIH-funded postdoctoral research associate positions

University of Connecticut

Connecticut
Posted 1 month ago

Two NIH-funded postdoctoral research associate positions are available at the Neuroengineering & Pain Research (NPR) lab in the University of Connecticut (UConn). A particular interest of the lab is to study sensory afferent neurophysiology and biomechanics of the visceral organs to reveal their contributing roles in mechanical visceral nociception; mechanical stimuli is the major modality to evoke pain from the visceral organs. Another research focus is to advance the science of neuromodulation as a non-drug alternative for managing chronic pain. The lab implements an integrative approach to study the neural encoding of sensory afferent endings, macro- and microscale biomechanics of distal colon and rectum, transcriptome assay of sensory afferent somata coupled with functional characterization, and multi-scale computational simulation of colorectal mechanical neural encoding. NPR lab benefits from being located in UConn School of Engineering to implement cutting-edge technologies in pain research, including customized fast GCaMP imaging system and data processing, microfabrication of electrode arrays for afferent recordings, nonlinear imaging with second harmonic generation, and machine learning-based signal processing. NPR lab also collaborates extensively with the Physiology & Neurobiology Department at UConn to implement state-of-the-art neuroscience research techniques, including mouse behavior assay of visceral pain, single-fiber extracellular recordings, sharp-electrode intracellular recordings, patch-clamp electrophysiology, cell culture, optogenetics, single-cell transcriptome assay, optical tissue clearing and immunohistochemistry.

 

Candidates should have a PhD in neuroscience, biomedical engineering, neurophysiology or a related discipline at the time of appointment. Exceptional candidates from other disciplines will be considered. Candidates are expected to have a fundamental understanding of the sensory nervous system. Highly preferred skill-sets include electrophysiological recordings from mammalian nervous systems, biomechanics, and/or single-cell molecular biology.

 

The responsibilities of the post-doctoral research associate will include: project development, data acquisition, analysis and evaluation, manuscript preparation, and presentation of findings at lab meetings and scientific conferences. The post-doctoral associate will also gain experience with grant writing and with mentoring more junior lab members. Appointment is for 3 years, with each year contingent upon satisfactory progress. Salary is commensurate with the NIH postdoctoral fellow pay scale. To apply, please send a cover letter briefly describing your research experience, a detailed CV, and the names and contact information for 3 references to Dr. Bin Feng at fengb@uconn.edu. Review of applications will begin immediately and will continue until both positions are filled.

 

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